A carregar...
Discovery of a novel kinase hinge binder fragment by dynamic undocking
One of the key motifs of type I kinase inhibitors is their interactions with the hinge region of ATP binding sites. These interactions contribute significantly to the potency of the inhibitors; however, only a tiny fraction of the available chemical space has been explored with kinase inhibitors rep...
Na minha lista:
| Publicado no: | RSC Med Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7593776/ https://ncbi.nlm.nih.gov/pubmed/33479656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00519f |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|