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Lost and Found: Re-searching and Re-scoring Proteomics Data Aids Genome Annotation and Improves Proteome Coverage

Prokaryotic genome annotation is heavily dependent on automated gene annotation pipelines that are prone to propagate errors and underestimate genome complexity. We describe an optimized proteogenomic workflow that uses ribosome profiling (ribo-seq) and proteomic data for Salmonella enterica serovar...

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Détails bibliographiques
Publié dans:mSystems
Auteurs principaux: Willems, Patrick, Fijalkowski, Igor, Van Damme, Petra
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593589/
https://ncbi.nlm.nih.gov/pubmed/33109751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00833-20
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