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Oral S-1 with 24-h Infusion of Irinotecan plus Bevacizumab versus FOLFIRI plus Bevacizumab as First-Line Chemotherapy for Metastatic Colorectal Cancer: An Open-Label Randomized Phase II Trial

BACKGROUND: FOLFIRI plus bevacizumab have been widely used as first-line treatment for metastatic colorectal cancer (mCRC). Pharmacokinetics and pharmacodynamics suggested a low dose of irinotecan given as a long-term infusion is expected to enhance antitumor activity. We conducted a randomized phas...

詳細記述

保存先:
書誌詳細
出版年:Oncology
主要な著者: Sadahiro, Sotaro, Suzuki, Toshiyuki, Okada, Kazutake, Saito, Gota, Miyakita, Hiroshi, Ogimi, Takashi, Chan, Lin Fung, Kamei, Yutaro
フォーマット: Artigo
言語:Inglês
出版事項: S. Karger AG 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592907/
https://ncbi.nlm.nih.gov/pubmed/32474564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000507293
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