Preventive treatment with ginsenoside Rb1 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats and involves store-operated calcium entry inhibition

CONTEXT: Ginsenoside Rb1, the main active ingredient of ginseng, exhibits ex vivo depression of store-operated calcium entry (SOCE) and related vasoconstriction in pulmonary arteries derived from pulmonary hypertension (PH) rats. However, the in vivo effects of ginsenoside Rb1 on PH remain unclear....

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Pharm Biol
Autori principali: Wang, Rui-Xing, He, Rui-Lan, Jiao, Hai-Xia, Zhang, Run-Tian, Guo, Jing-Yi, Liu, Xiao-Ru, Gui, Long-Xin, Lin, Mo-Jun, Wu, Zhi-Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2020
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592893/
https://ncbi.nlm.nih.gov/pubmed/33096951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2020.1831026
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