Amyloidogenic Nanoplaques in Cerebrospinal Fluid: Relationship to Amyloid Brain Uptake and Clinical Alzheimer’s Disease in a Memory Clinic Cohort

BACKGROUND: Aggregation of amyloid-β (Aβ) is an early pathological event in Alzheimer’s disease (AD). Consequently, measures of pathogenic aggregated Aβ are attractive biomarkers for AD. Here, we use a recently developed Thioflavin-T-Fluorescence Correlation Spectroscopy (ThT-FCS) assay to quantify...

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Bibliographische Detailangaben
Veröffentlicht in:J Alzheimers Dis
Hauptverfasser: Aksnes, Mari, Müller, Ebba Glersen, Tiiman, Ann, Edwin, Trine Holt, Terenius, Lars, Revheim, Mona-Elisabeth, Vukojević, Vladana, Bogdanović, Nenad, Knapskog, Anne-Brita
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592690/
https://ncbi.nlm.nih.gov/pubmed/32741818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200237
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