Novel strategy for manufacturing autologous dendritic cell/allogeneic tumor lysate vaccines for glioblastoma

BACKGROUND: Glioblastoma, the most common primary malignant brain tumor, is nearly universally fatal by 5 years. Dendritic cell vaccines are promising but often limited clinically by antigen choice, dendritic cell potency, and/or manufacturing yield. We optimized vaccine manufacture, generating pote...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Parney, Ian F, Gustafson, Michael P, Solseth, Mary, Bulur, Peggy, Peterson, Timothy E, Smadbeck, James B, Johnson, Sarah H, Murphy, Stephen J, Vasmatzis, George, Dietz, Allan B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592424/
https://ncbi.nlm.nih.gov/pubmed/33134920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa105
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