Mechanistic Target of Rapamycin Signaling Activation Antagonizes Autophagy To Facilitate Zika Virus Replication

Zika virus (ZIKV), a mosquito-transmitted flavivirus, is linked to microcephaly and other neurological defects in neonates and Guillain-Barré syndrome in adults. The molecular mechanisms regulating ZIKV infection and pathogenic outcomes are incompletely understood. Signaling by the mechanistic (mamm...

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Publicado en:J Virol
Autores principales: Sahoo, Bikash R., Pattnaik, Aryamav, Annamalai, Arun S., Franco, Rodrigo, Pattnaik, Asit K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Cellular Response to Infection
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592218/
https://ncbi.nlm.nih.gov/pubmed/32878890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01575-20
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