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Retinoic Acid Inducible Gene I and Protein Kinase R, but Not Stress Granules, Mediate the Proinflammatory Response to Yellow Fever Virus

Yellow fever virus (YFV) is an RNA virus primarily targeting the liver. Severe YF cases are responsible for hemorrhagic fever, plausibly precipitated by excessive proinflammatory cytokine response. Pathogen recognition receptors (PRRs), such as the cytoplasmic retinoic acid inducible gene I (RIG-I)-...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Beauclair, Guillaume, Streicher, Felix, Chazal, Maxime, Bruni, Daniela, Lesage, Sarah, Gracias, Ségolène, Bourgeau, Salomé, Sinigaglia, Laura, Fujita, Takashi, Meurs, Eliane F., Tangy, Frédéric, Jouvenet, Nolwenn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592215/
https://ncbi.nlm.nih.gov/pubmed/32878892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00403-20
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