MLAA-34 knockdown shows enhanced antitumor activity via JAK2/STAT3 signaling pathway in acute monocytic leukemia

MLAA-34 is a novel leukemia-associated gene closely related to the carcinogenesis of acute monocytic leukemia (AML). MLAA-34 over expression has been observed to inhibit apoptosis in vitro. JAK2/STAT3 pathway plays an important role in cell proliferation, differentiation and inhibition of apoptosis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cancer
Egile Nagusiak: Lei, Bo, Qian, Lu, Zhang, Yanping, Chen, Yinxia, Gao, Meili, Shah, Walayat, Cao, Xingmei, Zhang, Pengyu, Zhao, Wanhong, Liu, Jie, Wang, Jianli, Ma, Xiaorong, Yang, Yun, Meng, Xin, Cai, Fengmei, Xu, Yan, Luo, Jing, Wang, Baiyan, Zhang, Yang, He, Aili, Zhang, Wanggang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ivyspring International Publisher 2020
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592008/
https://ncbi.nlm.nih.gov/pubmed/33123268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.46670
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