Stratified layer analysis reveals intrinsic leptin stimulates cryptal mesenchymal cells for controlling mucosal inflammation

Mesenchymal cells in the crypt play indispensable roles in the maintenance of intestinal epithelial homeostasis through their contribution to the preservation of stem cells. However, the acquisition properties of the production of stem cell niche factors by the mesenchymal cells have not been well e...

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Udgivet i:Sci Rep
Main Authors: Matsumura, Seiichi, Kurashima, Yosuke, Murasaki, Sayuri, Morimoto, Masako, Arai, Fujimi, Saito, Yukari, Katayama, Nana, Kim, Dayoung, Inagaki, Yutaka, Kudo, Takahiro, Ernst, Peter B., Shimizu, Toshiaki, Kiyono, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591933/
https://ncbi.nlm.nih.gov/pubmed/33110098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75186-3
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