Pancreatic duct ligation reduces premalignant pancreatic lesions in a Kras model of pancreatic adenocarcinoma in mice

Pancreatic duct ligation (PDL) in the murine model has been described as an exocrine pancreatic atrophy-inducing procedure. However, its influence has scarcely been described on premalignant lesions. This study describes the histological changes of premalignant lesions and the gene expression in a w...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Cáceres, Marta, Quesada, Rita, Iglesias, Mar, Real, Francisco X., Villamonte, Maria, de Villarreal, Jaime Martinez, Pérez, Mónica, Andaluz, Ana, Moll, Xavier, Berjano, Enrique, Dorcaratto, Dimitri, Sánchez-Velázquez, Patricia, Grande, Luís, Burdío, Fernando
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591874/
https://ncbi.nlm.nih.gov/pubmed/33110094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74947-4
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