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Polymorphisms in STING Affect Human Innate Immune Responses to Poxviruses

We conducted a large genome-wide association study (GWAS) of the immune responses to primary smallpox vaccination in a combined cohort of 1,653 subjects. We did not observe any polymorphisms associated with standard vaccine response outcomes (e.g., neutralizing antibody, T cell ELISPOT response, or...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kennedy, Richard B., Haralambieva, Iana H., Ovsyannikova, Inna G., Voigt, Emily A., Larrabee, Beth R., Schaid, Daniel J., Zimmermann, Michael T., Oberg, Ann L., Poland, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591719/
https://ncbi.nlm.nih.gov/pubmed/33154747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.567348
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