Extracellular miR-574-5p Induces Osteoclast Differentiation via TLR 7/8 in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and joint destruction. Cell-derived small extracellular vesicles (sEV) mediate cell-to-cell communication in the synovial microenvironment by carrying microRNAs (miRs), a class of small non-coding RNAs....

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Udgivet i:Front Immunol
Main Authors: Hegewald, Anett B., Breitwieser, Kai, Ottinger, Sarah M., Mobarrez, Fariborz, Korotkova, Marina, Rethi, Bence, Jakobsson, Per-Johan, Catrina, Anca I., Wähämaa, Heidi, Saul, Meike J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591713/
https://ncbi.nlm.nih.gov/pubmed/33154755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.585282
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