CYP27B1 Downregulation: A New Molecular Mechanism Regulating EZH2 in Ovarian Cancer Tumorigenicity

BACKGROUND: Ovarian cancer has the highest mortality rate among gynecologic cancers, and most patients are diagnosed in advanced stages. Enhancer of zeste homolog 2 (EZH2) is a major tumor marker and an effective therapeutic target for ovarian cancer, but the underlying molecular mechanism remains u...

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Bibliografiska uppgifter
I publikationen:Front Cell Dev Biol
Huvudupphovsmän: Huo, Xiao, Sun, Hengzi, Qian, Qiuhong, Ma, Xiangwen, Peng, Peng, Yu, Mei, Zhang, Ying, Yang, Jiaxin, Cao, Dongyan, Gui, Ting, Shen, Keng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Cell and Developmental Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591459/
https://ncbi.nlm.nih.gov/pubmed/33163485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.561804
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