Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT

BACKGROUND: Novel chemotherapeutic drugs with good anti-tumor activity are of pressing need for bladder cancer treatment. In this study, plumbagin (PL), a natural plant-derived drug extracted from Chinese herbals, was identified as a promising candidate for human bladder cancer (BCa) chemotherapy. M...

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Bibliographic Details
Published in:Cancer Cell Int
Main Authors: Zhang, Renjie, Wang, Zijian, You, Wenjie, Zhou, Fengfang, Guo, Zicheng, Qian, Kaiyu, Xiao, Yu, Wang, Xinghuan
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590591/
https://ncbi.nlm.nih.gov/pubmed/33117085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01607-y
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