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Novobiocin inhibits membrane synthesis and vacuole formation of Enterococcus faecalis protoplasts

We demonstrate that plasma membrane biosynthesis and vacuole formation require DNA replication in Enterococcus faecalis protoplasts. The replication inhibitor novobiocin inhibited not only DNA replication but also cell enlargement (plasma membrane biosynthesis) and vacuole formation during the enlar...

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Bibliographic Details
Published in:Microb Cell
Main Authors: Tsuchikado, Rintaro, Kami, Satoshi, Takahashi, Sawako, Nishida, Hiromi
Format: Artigo
Language:Inglês
Published: Shared Science Publishers OG 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590531/
https://ncbi.nlm.nih.gov/pubmed/33150162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2020.11.735
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