Aptamers with Tunable Affinity Enable Single‐Molecule Tracking and Localization of Membrane Receptors on Living Cancer Cells

Tumor cell‐surface markers are usually overexpressed or mutated protein receptors for which spatiotemporal regulation differs between and within cancers. Single‐molecule fluorescence imaging can profile individual markers in different cellular contexts with molecular precision. However, standard sin...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Delcanale, Pietro, Porciani, David, Pujals, Silvia, Jurkevich, Alexander, Chetrusca, Andrian, Tawiah, Kwaku D., Burke, Donald H., Albertazzi, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590183/
https://ncbi.nlm.nih.gov/pubmed/32627326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202004764
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