Adjuvant Antitumor Immunity Contributes to the Overall Antitumor Effect of Pegylated Liposomal Doxorubicin (Doxil(®)) in C26 Tumor-Bearing Immunocompetent Mice

Doxorubicin (DXR) has been reported to have direct cytotoxicity against cancer cells and indirect immunotoxicity by modulation of host antitumor immunity. Hence, it may prevent cancer progression by a dual mechanism. Doxil(®), a formulation of DXR encapsulated in polyethylene glycol modified (PEGyla...

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Udgivet i:Pharmaceutics
Main Authors: Takayama, Takuma, Shimizu, Taro, Abu Lila, Amr S., Kanazawa, Yuki, Ando, Hidenori, Ishima, Yu, Ishida, Tatsuhiro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589973/
https://ncbi.nlm.nih.gov/pubmed/33086690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12100990
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