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Trastuzumab Modified Barium Ferrite Magnetic Nanoparticles Labeled with Radium-223: A New Potential Radiobioconjugate for Alpha Radioimmunotherapy

Barium ferrite nanoparticles (BaFeNPs) were investigated as vehicles for (223)Ra radionuclide in targeted α-therapy. BaFe nanoparticles were labeled using a hydrothermal Ba(2+) cations replacement by (223)Ra with yield reaching 61.3 ± 1.8%. Radiolabeled nanoparticles were functionalized with 3-phosp...

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Bibliografiske detaljer
Udgivet i:Nanomaterials (Basel)
Main Authors: Gawęda, Weronika, Pruszyński, Marek, Cędrowska, Edyta, Rodak, Magdalena, Majkowska-Pilip, Agnieszka, Gaweł, Damian, Bruchertseifer, Frank, Morgenstern, Alfred, Bilewicz, Aleksander
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589850/
https://ncbi.nlm.nih.gov/pubmed/33092037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano10102067
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