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Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease

The carboxyl-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) exerts a neuroprotective effect in neurodegenerative diseases via the activation of signaling pathways related to neurotrophins, and also through inhibiting apoptotic cell death. Here, we demonstrate that Hc-TeTx preserves mo...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Herrando-Grabulosa, Mireia, Casas, Caty, Talbot, Kevin, Aguilera, José
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589688/
https://ncbi.nlm.nih.gov/pubmed/33096857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12100666
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