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Y-27632 Induces Neurite Outgrowth by Activating the NOX1-Mediated AKT and PAK1 Phosphorylation Cascades in PC12 Cells

Y-27632 is known as a selective Rho-associated coiled coil-forming kinase (ROCK) inhibitor. Y-27632 has been shown to induce neurite outgrowth in several neuronal cells. However, the precise molecular mechanisms linking neurite outgrowth to Y-27632 are not completely understood. In this study, we ex...

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Pubblicato in:Int J Mol Sci
Autori principali: Park, So Yeong, An, Jeong Mi, Seo, Jeong Taeg, Seo, Su Ryeon
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589331/
https://ncbi.nlm.nih.gov/pubmed/33081375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207679
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