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What 20 years of research has taught us about the TP53 p.R337H mutation

The p53 tumor suppressor transcriptionally regulates a myriad of genes involved in cell cycle control, DNA repair, cell survival, and cell metabolism and represents one of the most well‐studied inhibitors of tumorigenesis. Since the discovery of TP53 in 1979, somatic mutations have been shown to be...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer
Prif Awduron: Pinto, Emilia Modolo, Zambetti, Gerard P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589304/
https://ncbi.nlm.nih.gov/pubmed/32875577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.33143
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