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Polysulfide and Hydrogen Sulfide Ameliorate Cisplatin-Induced Nephrotoxicity and Renal Inflammation through Persulfidating STAT3 and IKKβ

Cisplatin, a widely used chemotherapy for the treatment of various tumors, is clinically limited due to its extensive nephrotoxicity. Inflammatory response in tubular cells is a driving force for cisplatin-induced nephrotoxicity. The plant-derived agents are widely used to relieve cisplatin-induced...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sun, Hai-Jian, Leng, Bin, Wu, Zhi-Yuan, Bian, Jin-Song
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589167/
https://ncbi.nlm.nih.gov/pubmed/33096924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207805
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