Risk of Overcorrection in Rapid Intermittent Bolus vs Slow Continuous Infusion Therapies of Hypertonic Saline for Patients With Symptomatic Hyponatremia: The SALSA Randomized Clinical Trial

IMPORTANCE: Few high-quality studies have clarified whether hypertonic saline is best administered as slow continuous infusion (SCI) therapy or rapid intermittent bolus (RIB) therapy for symptomatic severe hyponatremia. OBJECTIVE: To compare the risk of overcorrection in RIB and SCI with hypertonic...

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Bibliographische Detailangaben
Veröffentlicht in:JAMA Intern Med
Hauptverfasser: Baek, Seon Ha, Jo, You Hwan, Ahn, Soyeon, Medina-Liabres, Kristianne, Oh, Yun Kyu, Lee, Jung Bok, Kim, Sejoong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Medical Association 2020
Schlagworte:
Original Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589081/
https://ncbi.nlm.nih.gov/pubmed/33104189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamainternmed.2020.5519
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