Alprostadil Injection Attenuates Coronary Microembolization-Induced Myocardial Injury Through GSK-3β/Nrf2/HO-1 Signaling-Mediated Apoptosis Inhibition

OBJECTIVE: Coronary microembolization (CME) results in progressive contractile dysfunction associated with cardiomyocyte apoptosis. Alprostadil injection improves microcirculation, which is effective in treating various cardiovascular disorders. However, the therapeutic effects of alprostadil in CME...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Qin, Zhenbai, Kong, Binghui, Zheng, Jing, Wang, Xiantao, Li, Lang
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588838/
https://ncbi.nlm.nih.gov/pubmed/33122886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S272877
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