Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases

Epigenetic dysregulation is a common mechanism shared by molecularly and clinically heterogenous neurodegenerative diseases (NDs). Histone acetylation homeostasis, maintained by the antagonistic activity of histone acetyltransferases (HATs) and histone deacetylases (HDACs), is necessary for appropri...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Beaver, Mariah, Bhatnagar, Akanksha, Panikker, Priyalakshmi, Zhang, Haolin, Snook, Renee, Parmar, Visha, Vijayakumar, Gayathri, Betini, Niteesha, Akhter, Sunya, Elefant, Felice
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588445/
https://ncbi.nlm.nih.gov/pubmed/33106538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75035-3
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