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Role of Glycosaminoglycans in Procathepsin B Maturation: Molecular Mechanism Elucidated by a Computational Study

[Image: see text] Procathepsins are an inactive, immature form of cathepsins, predominantly cysteine proteases present in the extracellular matrix (ECM) and in lysosomes that play a key role in various biological processes such as bone resorption or intracellular proteolysis. The enzymatic activity...

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Bibliografiset tiedot
Julkaisussa:J Chem Inf Model
Päätekijät: Bojarski, Krzysztof K., Karczyńska, Agnieszka S., Samsonov, Sergey A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2020
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588040/
https://ncbi.nlm.nih.gov/pubmed/32155059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.0c00023
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