Attenuation of a recombinant Marek's disease virus lacking the meq oncogene and evaluation on its immune efficacy against Marek's disease virus

SC9-2 is a recombinant Marek's disease virus (MDV) strain lacking the meq oncogene. Previous study demonstrated that SC9-2 virus provides good protection against challenge with a very virulent MDV rMd5, but it induces immunosuppressive effects in specific pathogen-free (SPF) chickens. In the pr...

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Bibliographic Details
Published in:Poult Sci
Main Authors: Sun, Peng, Cui, Ning, Liu, Linqing, Su, Shuai, Cheng, Ziqiang, Chen, Ruiai, Li, Yanpeng, Cui, Zhizhong
Format: Artigo
Language:Inglês
Published: Elsevier 2020
Subjects:
Immunology, Health and Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587640/
https://ncbi.nlm.nih.gov/pubmed/32241474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psj.2019.11.059
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