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Molecular Dynamic Simulations to Probe Stereoselectivity of Tiagabine Binding with Human GAT1

The human gamma aminobutyric acid transporter subtype 1 (hGAT1) located in the nerve terminals is known to catalyze the neuronal function by the electrogenic reuptake of γ-aminobutyric acid (GABA) with the co-transport of Na(+) and Cl(−) ions. In the past, there has been a major research drive focus...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zafar, Sadia, Jabeen, Ishrat
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587590/
https://ncbi.nlm.nih.gov/pubmed/33081136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204745
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