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Investigation of Dextran-Coated Superparamagnetic Nanoparticles for Targeted Vinblastine Controlled Release, Delivery, Apoptosis Induction, and Gene Expression in Pancreatic Cancer Cells

In the current study, the surface of superparamagnetic iron oxide (SPION) was coated with dextran (DEX), and conjugated with folic acid (FA), to enhance the targeted delivery and uptake of vinblastine (VBL) in PANC-1 pancreatic cancer cells. Numerous analyses were performed to validate the prepared...

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Publicat a:Molecules
Autors principals: Albukhaty, Salim, Al-Musawi, Sharafaldin, Abdul Mahdi, Salih, Sulaiman, Ghassan M., Alwahibi, Mona S., Dewir, Yaser Hassan, Soliman, Dina A., Rizwana, Humaira
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587551/
https://ncbi.nlm.nih.gov/pubmed/33076247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204721
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