Modeling of Chemoperfusion vs. Intravenous Administration of Cisplatin in Wistar Rats: Adsorption and Tissue Distribution

Hyperthermic intraperitoneal chemoperfusion (HIPEC) is an established form of locoregional chemotherapy of peritoneum tumors. However, its efficacy and safety status remain a controversy, partially, due to scarce data on pharmacokinetics and toxicity profile of drugs under HIPEC. In the current stud...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Kireeva, Galina, Kruglov, Stepan, Maydin, Mikhail, Gubareva, Ekaterina, Fedoros, Elena, Zubakina, Ekaterina, Ivanenko, Natalya, Bezruchko, Marina, Solovyev, Nikolay
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587530/
https://ncbi.nlm.nih.gov/pubmed/33076418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204733
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