Plasmodium falciparum Apicomplexan-Specific Glucosamine-6-Phosphate N-Acetyltransferase Is Key for Amino Sugar Metabolism and Asexual Blood Stage Development

UDP-N-acetylglucosamine (UDP-GlcNAc), the main product of the hexosamine biosynthetic pathway, is an important metabolite in protozoan parasites since its sugar moiety is incorporated into glycosylphosphatidylinositol (GPI) glycolipids and N- and O-linked glycans. Apicomplexan parasites have a hexos...

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Vydáno v:mBio
Hlavní autoři: Chi, Jordi, Cova, Marta, de las Rivas, Matilde, Medina, Ana, Borges, Rafael Junqueira, Leivar, Pablo, Planas, Antoni, Usón, Isabel, Hurtado-Guerrero, Ramón, Izquierdo, Luis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587441/
https://ncbi.nlm.nih.gov/pubmed/33082260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02045-20
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