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Cryptic or Silent? The Known Unknowns, Unknown Knowns, and Unknown Unknowns of Secondary Metabolism

Microbial natural products, particularly those produced by filamentous Actinobacteria, underpin the majority of clinically used antibiotics. Unfortunately, only a few new antibiotic classes have been discovered since the 1970s, which has exacerbated fears of a postapocalyptic world in which antibiot...

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Veröffentlicht in:mBio
Hauptverfasser: Hoskisson, Paul A., Seipke, Ryan F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587438/
https://ncbi.nlm.nih.gov/pubmed/33082252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02642-20
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