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Cryptic or Silent? The Known Unknowns, Unknown Knowns, and Unknown Unknowns of Secondary Metabolism

Microbial natural products, particularly those produced by filamentous Actinobacteria, underpin the majority of clinically used antibiotics. Unfortunately, only a few new antibiotic classes have been discovered since the 1970s, which has exacerbated fears of a postapocalyptic world in which antibiot...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Hoskisson, Paul A., Seipke, Ryan F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587438/
https://ncbi.nlm.nih.gov/pubmed/33082252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02642-20
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