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Cryptic or Silent? The Known Unknowns, Unknown Knowns, and Unknown Unknowns of Secondary Metabolism

Microbial natural products, particularly those produced by filamentous Actinobacteria, underpin the majority of clinically used antibiotics. Unfortunately, only a few new antibiotic classes have been discovered since the 1970s, which has exacerbated fears of a postapocalyptic world in which antibiot...

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Bibliographic Details
Published in:mBio
Main Authors: Hoskisson, Paul A., Seipke, Ryan F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587438/
https://ncbi.nlm.nih.gov/pubmed/33082252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02642-20
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