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Genome‐wide off‐rates reveal how DNA binding dynamics shape transcription factor function

Protein–DNA interactions are dynamic, and these dynamics are an important aspect of chromatin‐associated processes such as transcription or replication. Due to a lack of methods to study on‐ and off‐rates across entire genomes, protein–DNA interaction dynamics have not been studied extensively. Here...

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Detalles Bibliográficos
Publicado en:Mol Syst Biol
Main Authors: de Jonge, Wim J, Brok, Mariël, Lijnzaad, Philip, Kemmeren, Patrick, Holstege, Frank CP
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586999/
https://ncbi.nlm.nih.gov/pubmed/33280256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20209885
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