Oxidative stress modulates rearrangement of endoplasmic reticulum-mitochondria contacts and calcium dysregulation in a Friedreich's ataxia model

Friedreich ataxia (FRDA) is a neurodegenerative disorder characterized by neuromuscular and neurological manifestations. It is caused by mutations in the FXN gene, which results in loss of the mitochondrial protein frataxin. Endoplasmic Reticulum-mitochondria associated membranes (MAMs) are inter-or...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Rodríguez, Laura R., Calap-Quintana, Pablo, Lapeña-Luzón, Tamara, Pallardó, Federico V., Schneuwly, Stephan, Navarro, Juan A., Gonzalez-Cabo, Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585950/
https://ncbi.nlm.nih.gov/pubmed/33128998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101762
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