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An integrative multi-omics network-based approach identifies key regulators for breast cancer

Although genome-wide association studies (GWASs) have successfully identified thousands of risk variants for human complex diseases, understanding the biological function and molecular mechanisms of the associated SNPs involved in complex diseases is challenging. Here we developed a framework named...

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Veröffentlicht in:Comput Struct Biotechnol J
Hauptverfasser: Chen, Yi-Xiao, Rong, Yu, Jiang, Feng, Chen, Jia-Bin, Duan, Yuan-Yuan, Dong, Shan-Shan, Zhu, Dong-Li, Chen, Hao, Yang, Tie-Lin, Dai, Zhijun, Guo, Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Research Network of Computational and Structural Biotechnology 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585874/
https://ncbi.nlm.nih.gov/pubmed/33133424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.10.001
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