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Hippocampal neural stem cells are more susceptible to the neurotoxin BMAA than primary neurons: effects on apoptosis, cellular differentiation, neurite outgrowth, and DNA methylation

Developmental exposure to the environmental neurotoxin β-N-methylamino-l-alanine (BMAA), a proposed risk factor for neurodegenerative disease, can induce long-term cognitive impairments and neurodegeneration in rats. While rodent studies have demonstrated a low transfer of BMAA to the adult brain, t...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Pierozan, Paula, Cattani, Daiane, Karlsson, Oskar
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585576/
https://ncbi.nlm.nih.gov/pubmed/33099583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03093-6
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