Long interspersed nuclear element 1 hypomethylation has novel prognostic value and potential utility in liquid biopsy for oral cavity cancer

BACKGROUND: New biomarkers are urgently needed to improve personalized treatment approaches for head and neck squamous cell carcinoma (HNSCC). Global DNA hypomethylation has wide-ranging functions in multistep carcinogenesis, and the hypomethylation of long interspersed nucleotide element-1 (LINE-1)...

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Dettagli Bibliografici
Pubblicato in:Biomark Res
Autori principali: Misawa, Kiyoshi, Yamada, Satoshi, Mima, Masato, Nakagawa, Takuya, Kurokawa, Tomoya, Imai, Atsushi, Mochizuki, Daiki, Shinmura, Daichi, Yamada, Taiki, Kita, Junya, Ishikawa, Ryuji, Yamaguchi, Yuki, Misawa, Yuki, Kanazawa, Takeharu, Kawasaki, Hideya, Mineta, Hiroyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585304/
https://ncbi.nlm.nih.gov/pubmed/33110605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-020-00235-y
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