Genome-wide analysis of therapeutic response uncovers molecular pathways governing tamoxifen resistance in ER+ breast cancer

BACKGROUND: Prioritization of breast cancer patients based on the risk of resistance to tamoxifen plays a significant role in personalized therapeutic planning and improving disease course and outcomes. METHODS: In this work, we demonstrate that a genome-wide pathway-centric computational framework...

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Vydáno v:EBioMedicine
Hlavní autoři: Rahem, Sarra M., Epsi, Nusrat J., Coffman, Frederick D., Mitrofanova, Antonina
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585053/
https://ncbi.nlm.nih.gov/pubmed/33099086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103047
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