Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence

Relapse vulnerability in substance use disorder is attributed to persistent cue-induced drug seeking that intensifies (or “incubates”) during drug abstinence. Incubated cocaine seeking has been observed in both humans with cocaine use disorder and in preclinical relapse models. This persistent relap...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Werner, Craig T., Mitra, Swarup, Auerbach, Benjamin D., Wang, Zi-Jun, Martin, Jennifer A., Stewart, Andrew F., Gobira, Pedro H., Iida, Madoka, An, Chunna, Cobb, Moriah M., Caccamise, Aaron, Salvi, Richard J., Neve, Rachael L., Gancarz, Amy M., Dietz, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585028/
https://ncbi.nlm.nih.gov/pubmed/33020308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006133117
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