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An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase
VCP/p97, an enzyme critical to proteostasis, is regulated through interactions with protein adaptors targeting it to specific cellular tasks. One such adaptor, p47, forms a complex with p97 to direct lipid membrane remodeling. Here, we use NMR and other biophysical methods to study the structural dy...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7585011/ https://ncbi.nlm.nih.gov/pubmed/33028677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013920117 |
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