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Reduced striatal vesicular monoamine transporter 2 in REM sleep behavior disorder: imaging prodromal parkinsonism

Motor deficits in parkinsonism are caused by degeneration of dopaminergic nigral neurons. The success of disease-modifying therapies relies on early detection of the underlying pathological process, leading to early interventions in the disease phenotype. Healthy (n = 16), REM sleep behavior disorde...

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Publicado en:Sci Rep
Main Authors: Beauchamp, Leah C., Villemagne, Victor L., Finkelstein, David I., Doré, Vincent, Bush, Ashley I., Barnham, Kevin J., Rowe, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584593/
https://ncbi.nlm.nih.gov/pubmed/33097764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74495-x
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