Combination of syringaresinol–di–O–β-d-glucoside and chlorogenic acid shows behavioral pharmacological anxiolytic activity and activation of hippocampal BDNF–TrkB signaling

Mental stress, such as anxiety and conflict, causes physiological changes such as dysregulation of autonomic nervous activity, depression, and gastric ulcers. It also induces glucocorticoid production and changes in hippocampal brain-derived neurotrophic factor (BDNF) levels. We previously reported...

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Udgivet i:Sci Rep
Main Authors: Miyazaki, Shouhei, Fujita, Yoshio, Oikawa, Hirotaka, Takekoshi, Hideo, Soya, Hideaki, Ogata, Masato, Fujikawa, Takahiko
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584579/
https://ncbi.nlm.nih.gov/pubmed/33097741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74866-4
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