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Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis

Acquisition of a lipid-laden phenotype by immune cells has been defined in infectious diseases and atherosclerosis, but remains largely uncharacterized in cancer. Here, in breast cancer models we found that neutrophils are induced to accumulate neutral lipids upon interaction with resident mesenchym...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Li, Peishan, Lu, Ming, Shi, Jiayuan, Gong, Zheng, Hua, Li, Li, Qing, Lim, Bora, Zhang, Xiang H.-F., Chen, Xiaowen, Li, Sheng, Shultz, Leonard D., Ren, Guangwen
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584447/
https://ncbi.nlm.nih.gov/pubmed/32958928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0783-5
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