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Epidermal stem cell-derived exosomes promote skin regeneration by downregulating transforming growth factor-β1 in wound healing

BACKGROUND: Scar formation, which may be caused by myofibroblast aggregations, is the greatest challenge during skin wound healing in the clinical setting. Studies have indicated that epidermal stem cells (EPSC) improve wound healing and reduce scar formation. METHODS: We investigated the therapeuti...

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Библиографические подробности
Опубликовано в: :Stem Cell Res Ther
Главные авторы: Duan, Mengna, Zhang, Yan, Zhang, Haiyang, Meng, Yupeng, Qian, Ming, Zhang, Guokun
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584097/
https://ncbi.nlm.nih.gov/pubmed/33097078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01971-6
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