Effect of Oral Losartan on Orthobiologics: Implications for Platelet-Rich Plasma and Bone Marrow Concentrate—A Rabbit Study

Recent efforts have focused on customizing orthobiologics, such as platelet-rich plasma (PRP) and bone marrow concentrate (BMC), to improve tissue repair. We hypothesized that oral losartan (a TGF-β1 blocker with anti-fibrotic properties) could decrease TGF-β1 levels in leukocyte-poor PRP (LP-PRP) a...

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Pubblicato in:Int J Mol Sci
Autori principali: Nakama, Gilberto Y., Gonzalez, Sabrina, Matre, Polina, Mu, Xiaodong, Whitney, Kaitlyn E., Utsunomiya, Hajime, Arner, Justin W., Philippon, Marc J., Ravuri, Sudheer, Huard, Johnny
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584049/
https://ncbi.nlm.nih.gov/pubmed/33036225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197374
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