Self-Replication of Prion Protein Fragment 89-230 Amyloid Fibrils Accelerated by Prion Protein Fragment 107-143 Aggregates

Prion protein amyloid aggregates are associated with infectious neurodegenerative diseases, known as transmissible spongiform encephalopathies. Self-replication of amyloid structures by refolding of native protein molecules is the probable mechanism of disease transmission. Amyloid fibril formation...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Sneideris, Tomas, Ziaunys, Mantas, Chu, Brett K.-Y., Chen, Rita P.-Y., Smirnovas, Vytautas
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583978/
https://ncbi.nlm.nih.gov/pubmed/33049945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197410
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