PKM2 Determines Myofiber Hypertrophy In Vitro and Increases in Response to Resistance Exercise in Human Skeletal Muscle

Nearly 100 years ago, Otto Warburg investigated the metabolism of growing tissues and discovered that tumors reprogram their metabolism. It is poorly understood whether and how hypertrophying muscle, another growing tissue, reprograms its metabolism too. Here, we studied pyruvate kinase muscle (PKM)...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Verbrugge, Sander A. J., Gehlert, Sebastian, Stadhouders, Lian E. M., Jacko, Daniel, Aussieker, Thorben, M. J. de Wit, Gerard, Vogel, Ilse S. P., Offringa, Carla, Schönfelder, Martin, Jaspers, Richard T., Wackerhage, Henning
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583908/
https://ncbi.nlm.nih.gov/pubmed/32992783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197062
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