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Nexilin is necessary for maintaining the transverse-axial tubular system in adult cardiomyocytes.
BACKGROUND: Nexilin (NEXN) is a protein of the junctional membrane complex required for development of cardiac T-tubules. Global and cardiomyocyte specific loss of Nexn in mice leads to a rapidly progressive dilated cardiomyopathy and premature death. Therefore, little is known as to the role of NEX...
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| Veröffentlicht in: | Circ Heart Fail |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7583668/ https://ncbi.nlm.nih.gov/pubmed/32635769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.120.006935 |
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