Evaluation of Single-Cell Cytokine Secretion and Cell-Cell Interactions with a Hierarchical Loading Microwell Chip

Comprehensive evaluation of single T cell functions such as cytokine secretion and cytolysis of target cells is greatly needed in adoptive cell therapy (ACT) but has never been fully fulfilled by current approaches. Herein, we develop a hierarchical loading microwell chip (HL-Chip) that aligns multi...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Zhou, Yufu, Shao, Ning, de Castro, Ricardo Bessa, Zhang, Pengchao, Ma, Yuan, Liu, Xin, Huang, Feizhou, Wang, Rong-Fu, Qin, Lidong
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583657/
https://ncbi.nlm.nih.gov/pubmed/32348757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107574
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